Everolimus

by Team Onco
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Drug Name: Everolimus

Drug Class: It is a targeted therapy drug

Available under the brand name: Afinitor

What Is It Prescribed For?

  • Breast cancer
  • Kidney cancer 
  • Certain cancers of the pancreas, stomach, and intestines 
  • Lung cancer 
  • Kidney tumours in patients with Tuberous Sclerosis Complex (TSC; is an uncommon genetic disorder that causes the growth of tumours in many organs)
  • Subependymal giant cell astrocytoma (a type of brain tumour) that is associated with Tuberous Sclerosis Complex
  • Prevents transplant rejection in patients who have received kidney transplantation

How Is It Given?

It is available in tablet form and is taken by mouth, once or twice daily. It should be taken at around the same time with or without food.

What Are Common Side Effects?

You may face some of these side effects:

  • Abnormal physical weakness or lack of energy
  • Tiredness
  • Diarrhea or constipation
  • Dry mouth
  • Hair loss
  • Nose bleeds
  • Decrease in blood count
  • Painful mouth ulcers
  • Nausea and vomiting
  • Increased risk of infections
  • Skin rashes
  • Increased blood glucose levels

Your doctor can prescribe medication to control these side effects. Everolimus also causes other side effects. If you face any unusual or serious problems, inform your doctor immediately.

Who Should Avoid Taking This Drug?

It should be avoided in patients with known hypersensitivity to Everolimus or any of its ingredients.

How Much Does This Drug Cost?

Available in 0.25mg, 0.5mg, 5mg, 7.5mg, and 10mg tablets. Depending on the brand, the cost of Everolimus 10mg can range between INR 7000 – INR 30,000 per strip of 10 tablets.

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