What to Wear to Chemotherapy – Comfort Tips for Sessions

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Stay comfortable during chemotherapy with the right clothing. Learn what to wear for IV infusions, port access, and long treatment hours.

Chemotherapy is usually administered in cycles over several months. Depending on how the drugs are delivered — through an IV line or a port — you may need to make small adjustments to your clothing to stay comfortable during treatment.

Building a small, practical wardrobe for your chemotherapy sessions can make a big difference in your comfort and peace of mind.

Comfort Should Be the Priority

You may spend 2–6 hours (or more) in a clinic chair during each session. Choose soft, breathable, loose-fitting clothes that don’t restrict movement or press on your treatment site.

Tops to Wear

  • Button-down shirts or blouses: Ideal for easy access to IV lines in the arm.
  • V-neck or zip-front tops: Great for visibility and access if you have a port in your chest.
  • Loose T-shirts or tunics: Avoid tight necklines or sleeves that are hard to roll up.

Bottoms to Wear

  • Stretchy waistbands: Opt for leggings, sweatpants, or yoga pants.
  • Avoid belts or zippers: These can be uncomfortable when sitting for long periods.

Dress in Layers

Clinic temperatures vary, and some patients experience chills or hot flashes during treatment.

Bring a light sweater, cardigan, or shawl that you can easily remove or add. A soft blanket can also help you stay cozy.

Helpful Accessories

  • Comfortable socks or slippers: Keep feet warm and avoid cold floors.
  • Travel pillow: Supports your neck during long infusions.
  • Soft scarf: Can cover a port site or provide warmth.

What to Avoid

  • Tight clothing that restricts circulation
  • Fabrics that cause irritation (e.g., wool against sensitive skin)
  • Overly complicated outfits that are hard to take off
  • Jewelry near the IV or port site

Remember, there’s no “right” way to dress — the goal is to feel relaxed and supported. Choose clothes that make you feel like yourself, even on tough days.

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